Aries from Xena Warrior Princess he was just too awesome for words and he played minds games with Xena and put her through hell, and they had sizzling chemistry. But Xenaould always come up on top and kick his ass. EVERY TIME! I mean I know Xena was powerful and a great warrior but come on Aries was the God of War!! And he was getting his sexy little ass handed to him all the time by Xena. Just one fight or two I would like to see Aries wipe the floor with Xena.
Ah yes Aries, I loved Aries.
Venom from Spiderman, he just had the coolest suit and he was a nice touch of comic relief.
Drakken and Shego from Kim Possible. Poor Dr. Drakken, will he ever beat Kim? As for Shego I always liked her bad ass attitude and her outbursts at Drakken's incompitence.
The Troika from Buffy. I loved all three of them, little Jonathan, little Andrew and not so little Warren. I just love the underdogs, especially the nerdy ones and considering they weren't really that good as villains anyway.
Sniper Wolf from MGS. When I played this game as a kid, I always loved seeing sniper Wolf on screen. She was such a strong female character and the only female villain in the game, which made her more special.